The Chengdu-Chongqing region is located in the hinterland of southwest China, it is situated at the intersection of the "Belt and Road" and the Yangtze River Economic Corridor. The construction of the twin-city economic circle in the Chengdu-Chongqing region is a major national regional development strategy personally planned, deployed and promoted by General Secretary of CPC Xi Jinping. Historically, the Chengdu-Chongqing region has had unique advantages. After the founding of New China, it played a major role in the construction of the Third Line; since the reform and opening up, it has always been an important growth pole in the west. Entering the new era, the level of development is higher and the conditions are better. This paper examines and promotes the establishment of the "Belt and Road" foreign exchange center in the Chengdu-Chongqing region, shows that the foreign exchange Centre will accelerate the development of Chengdu-Chongqing into a "core city" of China's "Belt and Road" opening up to South Asia, Southeast Asia, Central Asia and even Europe.